Technology Overview

    Off line total and viable cell densityOff-line Total and Viable Cell Density Viable cell density monitoring with IncyteViable Cell Bio-Volume
with Incyte		 Total cell density monitoring with DencyteeVCD Soft Sensor with Incyte Arc Total cell density monitoring with DencyteeTotal Cell
Density with Dencytee		 viability with incyte dencytee sensorsViability with Incyte and Dencytee
Benefits and Attributes

Discrete Data Points

Sampling Required

Contamination Risk

Enables Process Control

Real-Time Decisions

Continuous Measurement

Reduce Sampling

✚

✚

High

✖

✖

✖

✖

✖

✖

Low

✚

✚

✚

✚

✖

✖

Low

✚

✚

✚

✚

✖

✖

Low

✚

✚

✚

✚

✖

✖

Low

✚

✚

✚

✚
Additional Benefits  
  • Cell Morphology Visualization
  • Growth Trend Interpolation
  • Detect Changes in Cell Size
  • Identify Apoptosis In-Situ
  • Online Calculation of Viable Cell Density that Correlates to Offline Measurement
  • Temperature Independent Total Cell Density Measurement
  • Online Viability Estimation
Measurement Output  
  • Cell Count (cells mL-1)
  • Cell Viability (%)
  • Other Complex Measurements
  • Viable Cell Volume Expressed as Permittivity (pF/cm)
  • Viable Cell Count via Soft Sensor (Cells mL-1
  • Viable Cell Volume Expressed as Permittivity (pF/cm)
  • Total Cell Density Expressed as OD, AU, g L-1, Cells ml-1, NTU, arb.
    Unit, CFU, OD, PCV
  • Viability (%)
Requirements  
  • Cell Counter and Chemicals
  • Off-line Samples
  • Operator
  • Sample Preparation
  • Incyte Arc Sensor
  • ArcAirTM
  • No Transmitte